Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities
Soft matter science and the COVID-19 pandemic
Jackie Chan, a kung fu star and a member of the CPPCC National Committee, raised his experiences about smoking bans in China and Singapore as an example. During a business trip, his colleagues still smoked after a warning from a security guard in Zhuhai, Guangdong province, but they didn't dare smoke when they arrived in Singapore because "it was strict about smoking there".
Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
其实，在第一部iPhone手机发布的前一年，LG集团已经推出了全触屏手机。虽然那也不是第一台触屏手机。1992年，世界上第一台触屏手机IBM Simon发布。而触屏技术在"西蒙"之前已经出现。1965年，E·A·约翰逊发明了第一个触屏设备——平板电脑，截止到1995年，一直由空中交通管制员使用。本特·斯顿普和弗兰克·贝克(Frank Beck)在20世纪70年代早期发明了电容式触屏，与约翰逊所发明触屏不同的是，它不能用手指操作，而是需要使用触控笔。在1971年，山姆·赫斯特发明了第一台电阻式触屏，他称之为"电子图表"。手指和触控笔都可以对它进行操作。在1985年，惠普公司发明了世界上第一台触屏电脑H-P150。在1993年，苹果公司也发布了第一个触屏设备——牛顿个人电子助理设备。但此产品并不成功，它的销量很低。
Average years of work experience: 12 years
St. Vincent “Digital Witness” (Loma Vista/Republic)
Trends and targets in antiviral phototherapy
According to the announcement, the new administrative center in Tongzhou will put infrastructure upgrades and ecological improvement on top of the agenda. The municipal government hopes to improve public services in education, healthcare, cultural events and industries in the district.
Though its campuses often steal the benefits spotlight -- with their outdoor sports facilities, free food and more -- there's a more morbid perk that should certainly be noted. If a U.S. Googler passes away while working for the tech giant, the employee's spouse or domestic partner receives 50% of the deceased's salary, no matter how long or short his tenure, every year for the next decade.
A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
6. "How I Met Your Mother" (3.0 million)
Novel biosensing methodologies for ultrasensitive detection of viruses
Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
ACE2 as a potential therapeutic target for pandemic COVID-19
Diagnostic technologies for COVID-19: a review
Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
While Insead’s joint programme dropped back into second place, its single-school programme moved up three places to fourth, a place it last occupied in 2011.
Trailing behind "Game of Thrones" on the most downloaded list are "Breaking Bad" and "The Walking Dead." Here is the list of 2013's most-downloaded TV shows (single episode) according to data collected by TorrentFreak and BitTorrent trackers:
The identity of the people buried in the cemetery is a mystery. The cemetery had been robbed in the past and no writing was found that indicates the names of those buried or their positions in life.
An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Puerto Ricans have been hit with dozens of new taxes in the past four years and increases in utility bills as former Gov. Alejandro Garcia Padilla aimed to generate more revenue for a government he said was running out of money. Despite those and other measures, the island’s government has defaulted on millions of dollars’ worth of bond payments and declared a state of emergency at several agencies.
Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Saif held the highest position among the five ranked Chinese schools, just ahead of Guanghua School of Management and Tsinghua University School of Economics and Management, 17th and 18th respectively.
Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Antiviral drug discovery: broad-spectrum drugs from nature
As stars such as Kevin Spacey and Morgan Freeman were alleged to have assaulted or harassed performers, activists began using the hashtag to share their ordeals online.
I used to think guff was a product of failure and mediocrity — it existed because the truth was too painful, or because executives had not bothered to ascertain what the truth was.
Influenza neuraminidase: A druggable target for natural products
China’s trade with the rest of the world fell sharply in October from a year earlier, with imports of raw materials particularly hard hit as slowing Chinese investment feeds through into weaker demand in the world’s biggest trader of goods.
都柏林大学学院(UCD)迈克尔?斯墨菲特商业研究生院(Michael Smurfit Graduate School of Business)的总体进步最大，排名攀升21位至第48名。北京大学(Peking University)光华管理学院(Guanghua School of Management)重回排行榜第38名，去年该院因学员调查反馈率低而未上榜。
Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Federal, state and local government job cutbacks are slowing. More than 250,000 workers at all levels of government lost jobs last year. This year, so far, about 20,000 have gained jobs. Worries about the nation's debt and deficits likely will keep a lid on government spending and investments, economists say, but any jumps in, say, infrastructure spending would create jobs. At the least, government will be less of a drag.[qh]
The role of biosensors in the detection of emerging infectious diseases
Quantitative determination of mechanical stability in the novel coronavirus spike protein
Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
adj. 全国流行的 n. (全国或全世界范围流行的)疾
No matter whether you’re looking for big international events, delicious food, natural wonders or simply relaxation on a beach, these places should be on your checklist.
The EU’s Americas gambits
MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
两次发生在洛杉矶的反抗时间之旅。两次对女人之间时而棘手的团结的赞颂。四位演员的精彩表演，来自吉塔娜·基基·罗德里格斯(Kitana Kiki Rodriguez)、米娅·泰勒(Mya Taylor)、茱莉亚·加纳，以及了不起的莉莉·汤姆林。《与外婆同行》是制片公司资深导演的作品，《橘色》是用iPhone手机拍摄。任何哀悼电影已死的人，都应该闭上嘴巴，看看这两部影片。
Justin Bieb er just made tens of thousands of more dollars -- from his hair. The 'Baby' singer's locks sold on eBay yesterday with a final bid of $40,688.
Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Haruhiko Kuroday, the Japanese central bank governor said: “I think we can be cautiously optimistic about the global outlook.
Inhibition of SARS coronavirus helicase by bismuth complexes
"Those who disrupt testing and harm the equity of education by cheating will get the punishment they deserve," the ministry said.
Most of the cellphones sold in 2016 are smart phones installed with the Android system and 4G ready, according to the report.
The most staggering scene is, of course, that in which the alien picks up a young man with the facial condition neurofibromatosis, played by Adam Pearson. Glazer brings to this scene an utter fearlessness and unsentimentality, perhaps a variation on a theme from David Lynch’s The Elephant Man. The alien does not essentially distinguish between his looks and those of her other victims, but her encounter with him – an encounter of two aliens? – triggers a crisis in which she becomes the prey rather than the hunter.
Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
But now she's using her storybook looks for good, dressing up as the character to entertain children and cheer-up cancer patients.
Bolder lawyers will start working with more “sci-fi” programs that claim to predict the outcomes of legal disputes before they have reached court, by analysing similar cases and past rulings, opposition tactics and win/lose statistics, the success rates of certain lawyers before certain judges, and so on.
Overall, starting a company ranked lowest among reasons cited for undertaking an EMBA (rated 5.5 out 10). Students’ main motivations were learning about management (9.1), networking (8.3) and increasing earnings (8.1).
A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
The two pleasure devices both made of bronze date back more than 2000 years to China's Han Dynasty (206 BC–220 AD).
Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.
Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.
Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Washington's twin-obsessions in election year 2010 will be to create jobs and cut the deficit. Little will be accomplished on either count.
Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Wang Jianlin, the entertainment mogul behind a series of high-profile acquisitions in Hollywood, and internet tycoon Jack Ma retained their spots at the top of the list, with fortunes of $32.1bn and $30.6bn respectively.
节目4 小品《我要上春晚》，周炜 刘大成 石头 张尧等
A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring
Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
That's part of the logic, anyway, behind the unlikely candidacy of Ethan Sonneborn, a 13-year-old running for governor of Vermont, one of just two states with no minimum age requirement for the office.
Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
When it comes to diversity, I am optimistic that at some point the rise of enlightened younger executives will trigger a sudden change of attitude in the boardroom. This will not happen in 2018, though the imbalances and abuses of power evident in sexual harassment scandals, from tech to media, could accelerate change.
The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
China in 2012: fixated on stability as the pressures mount without and within.
Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
It is based on a survey of business schools and another of their alumni who graduated in 2013.
Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Skin has the thankless job of coating and protecting your whole body, making it your most easily damaged organ. When you burn or rip off a stretch of skin, your main option right now is to graft some back on from elsewhere on your body. But an effective synthetic replacement skin may not be that far off, thanks to research from Stanford scientists.
Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Over the three-year period we examined, late arrivals actually declined during the Thanksgiving travel season — just 12 percent of Thanksgiving flights were delayed last year, compared with 19 percent in 2010. according to the Transportation Department.
Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
It is also reported that Chinese citizens made 1.26 billion cinema visits in 2015, a roughly 51 percent increase from a year earlier.
The company realised that "it was all a mistake and that he did it without thinking," a Google spokeswoman said last Wednesday.
Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Supporting Actress in a Comedy: Kate McKinnon, “Saturday Night Live”
Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
It predicts index funds, or those that track commodities indices, to be back in the agricultural market in the second half of 2017, as they look for a hedge against inflation.
Better still was Iain Roberts, global managing director of the design company Ideo, who asked a question to which I hope never to hear the answer: “How to activate insights around latent mobility or multimodal needs?”
Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Anyone can have a bad day at the office, but this disappointing performance at Christie’s followed an old masters sale in July that took in 19 million against a low estimate of 31.5 million.
Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.
Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.
Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.
Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
人力资源机构罗伯特?哈夫国际公司（Robert Half International）最近针对4,000名企业高管进行了一项调研。其中有88%的人预计，未来一年，公司的业务将有所好转。这不失为最鼓舞人心的消息了。
According to the country's film regulator, China's box office sales have boosted a whopping 48.7 percent in the last year alone.
A modular microarray imaging system for highly specific COVID-19 antibody testing
Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.
Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.
Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
We will make a big push for progress in the reform of the social system.
Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
A facile assay for rapid detection of COVID-19 antibodies
Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Vawter climbed 103 floors of a Chicago skyscraper on his bionic leg, but its designers are still working on improving it. To optimize it for everyday use, they have to make it even thinner and lighter. Its successor (the iLeg Air?) may meet the Army's stated goal for a bionic leg—10,000 steps without recharging.
Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Remedy: The tricky aspect of this regret is that it’s typically rooted in hindsight. Only after you’ve left the job and have moved on to something better, do you start beating yourself up for not making the leap sooner, even if it hadn’t been practical or possible. What you can do is to identify the factors that kept you in your former position as red flags to be aware of in the future and work to line up supports that will allow you to more quickly capitalize on other opportunities as they may present themselves. This could include reviewing and updating your resume with new accomplishments on a monthly or quarterly basis, keeping your LinkedIn account current, building up a contingency fund to allow you to feel less tethered to your current pay check and staying in the loop on industry news and gossip to be aware of where your skills and experience could be of value.
On 2 March, the North's state-run website Uriminzokkiri warned that Pyongyang would respond to any balloon launches with "not just a few shots of gunfire but cannons or missiles".
For the first time in six years, a new challenger has topped the FT’s ranking of executive MBA programmes.
Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Last year, only 930,000 of the 1.39 million qualified finally entered the exam halls.
Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.
Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Anti-HIV drug repurposing against SARS-CoV-2
实际上，去年新出炉的炒鱿鱼委婉用语(euphemisms for firing people)跟往年的产量差不多。Infosys宣称“井然有序地实现了一次3000人的人员递减”。Upworthy，一家规模不大的媒体公司，在解雇了14名员工后竟然大言不惭地称这是一次“投资性裁员”。反言之，2016年最极品的行话体现出的不是失败，而是兴奋过头。
Length-scale dependence of protein hydration-shell density
Take solid and effective steps to cut overcapacity
Are you looking at the clothes? Eva Longoria Parker stripped off as she posed with husband Tony to advertise the London Fog fashion line. Eva Longoria Parker s
Type A and Type B personality theory describes Type A individuals as outgoing, ambitious, rigidly organized, highly status-conscious, sensitive, impatient, anxious, proactive, and concerned with time management.
High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Klay Thompson added 19 points and Andrew Bogut scored 13 for the Warriors, off to the best start by an NBA team since Dallas won its first 14 games in 2002-03. Golden State needs three wins to equal the league record of 15-0, held by the 1948-49 Washington Capitols and 1993-94 Houston Rockets.
A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
Mr Draghi hit back the day after the December vote, saying that there was no “limit” to what eurozone policymakers could do to return inflation to its target.
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According to the China Auto Dealers Chamber of Commerce, which is helping to organise the dealers, Hyundai’s import-only dealer network has already halved in size since 2014.